4F-MPH (4-Fluoromethylphenidate) is a novel synthetic stimulant of the substituted phenethylamine and piperidine classes, that is said to produce a long-lasting euphoriant, and stimulating effect. It is a closely related structural analog of the commonly prescribed ADHD drug methylphenidate.
The two substances are believed to have very similar pharmacological mechanisms as monoamine reuptake inhibitors but have been reported to display distinctive subjective effects, with 4F-MPH being considered significantly more euphoric and recreational. Anecdotal reports suggest that it is considerably more potent with fewer uncomfortable side effects such as anxiety, muscle spasms and compulsive redosing. This perhaps owes to the fact that it has been shown to act as a higher efficiency dopamine reuptake inhibitor than the parent compound methylphenidate.