Effects and Working Mechanism of Thiopropamine Research Chemical

Posted by in on September 20, 2016 . .

Thiopropamine Facts:

  • Systematic (IUPAC) name: 1-(thiophen-2-yl)-2-aminopropane
  • Molecular Formula: C7H11NS 
  • Average mass: 141.234 Da
  • Molecular mass: 141.23 g/mol



Thiopropamine is a stimulant drug, which is an analogue of amphetamine where the phenyl ring has been replaced by thiophene. Its synthesis dates back to 1942. The N-methyl and thiophen-3-yl analogues of thiopropamine are also known, but are generally weaker than the corresponding amphetamines. Thiopropamine has similar stimulant effects but has one third potency as compared to amphetamine.

Thiopropamine has reached the global research scene and can be found in scientific literature under its full IUPAC designation 1-(thiophen-2-yl)-2-aminopropane. The physical appearance of the product is white fluffy powder and is legal in most jurisdictions only for in vitro scientific research. Thiopropamine is an analogue of amphetamine where the phenyl ring has been replaced by thiophene, which is a hytrocylic compound with the formula C4H4S.

Thiopropamine Effects

Thiopropamine being a psychoactive drug stimulates the performance of mental or physical functions. It enhances the alertness and wakefulness in human beings. It is structured on the analogue of amphetamine. It is most likely to act as norepinephrine-dopamine reuptake inhibitor. It is also a stimulant that is applied to cure diseases including narcolepsy, obesity and attention deficit hyperactivity disorder (ADHD). Thiopropamine is known to increase excitement, happiness and unwind hypertension.

How to get Research Chemicals Online

Metabolisation of Thiopropamine

Thiopropamine is metabolised into active 4-hydroxymethiopropamine and thiophene S-oxides. It is further deaminated by CYP2C in liver transforming them into inactive 1-(Thiophen-2-yl)-2-propan-2-one.


This research chemical is sold only for research uses in laboratory settings by online research chemical suppliers. All standard precautions for laboratory work should be applied, while experiments are conducted using thiopropamine. You must ascertain local regulations before placing an order for thiorproamine at online research chemical store.