Research Chemicals Blog

Posted by in on Jan 18, 2017 .
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Posted by in on Sep 21, 2016 .

Research chemicals (also known as designer drugs) are chemically altered forms of psychoactive drugs, ecstasy amphetamines and cannabinoids. They are structurally similar to scheduled drugs and can be called their analogues. On the contrary, entheogens legal highs are natural plant extracts. These herbal highs have been used by people for recreational purposes for thousands of years. These are just the simple definitions for these two variants of compounds. Read on to find out the main differences between research chemicals and entheogens.

Research chemicals

  • Research chemicals are mainly used for scientific & research...

Posted by in on Sep 20, 2016 .

Thiopropamine Facts:

  • Systematic (IUPAC) name: 1-(thiophen-2-yl)-2-aminopropane
  • Molecular Formula: C7H11NS 
  • Average mass: 141.234 Da
  • Molecular mass: 141.23 g/mol

                    

INTRODUCTION

Thiopropamine is a stimulant drug, which is an analogue of amphetamine where the phenyl ring has been replaced by thiophene. Its synthesis dates back to 1942. The N-methyl and thiophen-3-yl analogues of thiopropamine are also known, but are generally weaker than the corresponding amphetamines. Thiopropamine has similar stimulant effects but has one third potency as compared to amphetamine.

Thiopropamine has reached the...

Posted by in on Aug 10, 2016 .

Nifoxipam research chemical belongs to the class of benzodiazepine chemical group and is a minor metabolite of flunitrazepam. Nifoxipam has tranquillising and sleep-prolonging effects on human body and has much lower toxicity as compared to flunitrazepam and lormetazepam.

  • IUPAC Name: 3-hydroxydesmethylflunitrazepam, DP 370
  • Molar Mass: 315.256 g/mol 
  • Formula: C15H10FN3O4

                                                                       

Chemistry of Nifoxipam

Nifoxipam contains a benzene ring fused to a diazepine ring. It is an active metabolite of flunitrazepam. The benzyl ring of nifoxipam is substituted at R7...

Posted by in on Aug 05, 2016 .

4-Fluoromethylphenidate (4F-MPH) is a stimulant drug that acts as a higher efficiency dopamine reuptake inhibitor than its close analogue methylphenidate. It was initially developed as a replacement for ethylphenidate. Anecdotal reports suggest that 4F-MPH is considerably more potent with fewer side effects.

IUPAC Name: Methyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate

Molecular Formula: C14H18FNO2

Molar Mass: 251.3 g/mol

                                                                                                        Structure of 4F-MPH

Higher Binding Potency

A study has found that the meta- and...

Posted by in on Jul 26, 2016 .

INTRODUCTION

The chemical 'cathinone' is a stimulant drug which occurs naturally in the plant called Khat. Synthetic cathinones are β-keto phenethylamines and chemically they are similar to amphetamine and methamphetamine. Synthetically produced chemicals such as mephedrone, methylone (M1) and MDPV – all fall under the cathinones chemical group. The principal active ingredient found in the leaves of the khat plant (catha edulis) is used for synthesizing a range of synthetic cathinones.

  • Chemical formula: C9H11NO
  • Molar Mass: 149.19g/mol
  • Chemical Name: (S)-2-Amino-1-phenyl-1-propanone
  • Common Name: Bath...

Posted by in on Jun 21, 2016 .

Alpha-Methyltryptamine: Introduction

Alpha-Methyltryptamine (AMT) is a potent stimulant, enactogen and psychedelic research chemical that belongs to the family of tryptamine. The chemical was originally developed at a Michigan pharmaceutical manufacturing company known as Upjohn as an antidepressant in the 1960s. This pharmaceutical drug was previously sold under the name Indopan in the Soviet Union. It has molecular formula of C11H14N2 while IUPAC name is 1-(1H-Indol-3-yl)propan-2-amine and molar mass is 174.24 g/mol.

Structure of AMT

                                                                                               ...

Posted by in on Jun 10, 2016 .

Introduction

IUPAC Name: 5-[Ethoxy-5-[2-(4-ethyl-piperazin-1-yl)-acetyl]-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one
Molecular Formula: C25H34N6O3
Molecular Weight: 466.57586 g/mol
Common Names: Hongdenafil or sildenafil

Description

Acetildenafil is a synthetic drug which is known to act as a phosphodiesterase inhibitor. It is an analogue of sildenafil (Viagra) and appears to boost libido and alleviate erectile dysfunction. Since,  Acetildenafil inhibits phosphodiesterase enzyme, it can be used to regulate intracellular levels of the second messengers cAMP and cGMP, and cell function.

Effects of...